amg 510 Search Results


5s 4  (Enamine Ltd)
90
Enamine Ltd 5s 4
5s 4, supplied by Enamine Ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/amg+510/AMG-510/pmc08041284__ja0c10644_si_002-2-2-8
Average 90 stars, based on 1 article reviews
5s 4 - by Bioz Stars, 2026-10
90/100 stars
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amg 510  (MedChemExpress)
96
MedChemExpress amg 510
Benchmarking of top compound 1 in several cancer cell lines. (A) The relative 2D viability of various cell lines following single dose treatment <t>with</t> <t>AMG-510</t> (1 μM), calmidazolium (2.5 μM), OphA (1 μM), and 1 (10 μM) was assessed using the alamarBlue assay. Cells were grown as 2D adherent monolayers overnight and then treated for 72 h with indicated compounds. Data represent mean values ± SD, n ≥ 3. (B) DSS 3 measuring the effects of AMG-510 (0.003–40 μM), calmidazolium (0.3–40 μM), OphA (0.3–40 μM), and 1 (0.6–80 μM). Cells were grown as 2D adherent monolayers overnight and then treated for 72 h. Results represent mean values ± SD, n = 3. (C) DSS 3 measuring the effects of AMG-510 (0.6–40 μM), vemurafenib (0.3–20 μM), prostratin (0.6–80 μM), OphA (0.3–20 μM), and 1 (1.3–80 μM). Cells were grown as 3D spheroids for 72 h then treated with compounds for another 72 h before alamarBlue viability measurements. Data represent mean values ± SD, n ≥ 2. (D) Heatmap of ATARiS gene sensitivity scores obtained from the project DRIVE database for KRAS-dependent cell lines (MIA PaCa-2, NCI H358, and MDA-MB-231) and HRAS-dependent cell lines (Hs 578T and T24). Negative values (red) indicate sensitivity of the cell line proliferation to the knockdown of shown genes, while positive (blue) indicates the opposite.
Amg 510, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/amg+510/Sotorasib/pmc08296985-34-0-2
Average 96 stars, based on 1 article reviews
amg 510 - by Bioz Stars, 2026-10
96/100 stars
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sotorasib amg510  (MedChemExpress)
95
MedChemExpress sotorasib amg510
Benchmarking of top compound 1 in several cancer cell lines. (A) The relative 2D viability of various cell lines following single dose treatment <t>with</t> <t>AMG-510</t> (1 μM), calmidazolium (2.5 μM), OphA (1 μM), and 1 (10 μM) was assessed using the alamarBlue assay. Cells were grown as 2D adherent monolayers overnight and then treated for 72 h with indicated compounds. Data represent mean values ± SD, n ≥ 3. (B) DSS 3 measuring the effects of AMG-510 (0.003–40 μM), calmidazolium (0.3–40 μM), OphA (0.3–40 μM), and 1 (0.6–80 μM). Cells were grown as 2D adherent monolayers overnight and then treated for 72 h. Results represent mean values ± SD, n = 3. (C) DSS 3 measuring the effects of AMG-510 (0.6–40 μM), vemurafenib (0.3–20 μM), prostratin (0.6–80 μM), OphA (0.3–20 μM), and 1 (1.3–80 μM). Cells were grown as 3D spheroids for 72 h then treated with compounds for another 72 h before alamarBlue viability measurements. Data represent mean values ± SD, n ≥ 2. (D) Heatmap of ATARiS gene sensitivity scores obtained from the project DRIVE database for KRAS-dependent cell lines (MIA PaCa-2, NCI H358, and MDA-MB-231) and HRAS-dependent cell lines (Hs 578T and T24). Negative values (red) indicate sensitivity of the cell line proliferation to the knockdown of shown genes, while positive (blue) indicates the opposite.
Sotorasib Amg510, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/amg+510/Sotorasib/pmc10920083-38-0-5
Average 95 stars, based on 1 article reviews
sotorasib amg510 - by Bioz Stars, 2026-10
95/100 stars
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amg 510  (CH Instruments)
90
CH Instruments amg 510
Benchmarking of top compound 1 in several cancer cell lines. (A) The relative 2D viability of various cell lines following single dose treatment <t>with</t> <t>AMG-510</t> (1 μM), calmidazolium (2.5 μM), OphA (1 μM), and 1 (10 μM) was assessed using the alamarBlue assay. Cells were grown as 2D adherent monolayers overnight and then treated for 72 h with indicated compounds. Data represent mean values ± SD, n ≥ 3. (B) DSS 3 measuring the effects of AMG-510 (0.003–40 μM), calmidazolium (0.3–40 μM), OphA (0.3–40 μM), and 1 (0.6–80 μM). Cells were grown as 2D adherent monolayers overnight and then treated for 72 h. Results represent mean values ± SD, n = 3. (C) DSS 3 measuring the effects of AMG-510 (0.6–40 μM), vemurafenib (0.3–20 μM), prostratin (0.6–80 μM), OphA (0.3–20 μM), and 1 (1.3–80 μM). Cells were grown as 3D spheroids for 72 h then treated with compounds for another 72 h before alamarBlue viability measurements. Data represent mean values ± SD, n ≥ 2. (D) Heatmap of ATARiS gene sensitivity scores obtained from the project DRIVE database for KRAS-dependent cell lines (MIA PaCa-2, NCI H358, and MDA-MB-231) and HRAS-dependent cell lines (Hs 578T and T24). Negative values (red) indicate sensitivity of the cell line proliferation to the knockdown of shown genes, while positive (blue) indicates the opposite.
Amg 510, supplied by CH Instruments, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/amg+510/amg+510/pmc08894142-150-4-38
Average 90 stars, based on 1 article reviews
amg 510 - by Bioz Stars, 2026-10
90/100 stars
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s7-amg-510  (Canon inc)
90
Canon inc s7-amg-510
Benchmarking of top compound 1 in several cancer cell lines. (A) The relative 2D viability of various cell lines following single dose treatment <t>with</t> <t>AMG-510</t> (1 μM), calmidazolium (2.5 μM), OphA (1 μM), and 1 (10 μM) was assessed using the alamarBlue assay. Cells were grown as 2D adherent monolayers overnight and then treated for 72 h with indicated compounds. Data represent mean values ± SD, n ≥ 3. (B) DSS 3 measuring the effects of AMG-510 (0.003–40 μM), calmidazolium (0.3–40 μM), OphA (0.3–40 μM), and 1 (0.6–80 μM). Cells were grown as 2D adherent monolayers overnight and then treated for 72 h. Results represent mean values ± SD, n = 3. (C) DSS 3 measuring the effects of AMG-510 (0.6–40 μM), vemurafenib (0.3–20 μM), prostratin (0.6–80 μM), OphA (0.3–20 μM), and 1 (1.3–80 μM). Cells were grown as 3D spheroids for 72 h then treated with compounds for another 72 h before alamarBlue viability measurements. Data represent mean values ± SD, n ≥ 2. (D) Heatmap of ATARiS gene sensitivity scores obtained from the project DRIVE database for KRAS-dependent cell lines (MIA PaCa-2, NCI H358, and MDA-MB-231) and HRAS-dependent cell lines (Hs 578T and T24). Negative values (red) indicate sensitivity of the cell line proliferation to the knockdown of shown genes, while positive (blue) indicates the opposite.
S7 Amg 510, supplied by Canon inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/amg+510/s7+amg+510/pmc07680331-7-5-7
Average 90 stars, based on 1 article reviews
s7-amg-510 - by Bioz Stars, 2026-10
90/100 stars
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amg 510  (Amgen)
86
Amgen amg 510
Benchmarking of top compound 1 in several cancer cell lines. (A) The relative 2D viability of various cell lines following single dose treatment <t>with</t> <t>AMG-510</t> (1 μM), calmidazolium (2.5 μM), OphA (1 μM), and 1 (10 μM) was assessed using the alamarBlue assay. Cells were grown as 2D adherent monolayers overnight and then treated for 72 h with indicated compounds. Data represent mean values ± SD, n ≥ 3. (B) DSS 3 measuring the effects of AMG-510 (0.003–40 μM), calmidazolium (0.3–40 μM), OphA (0.3–40 μM), and 1 (0.6–80 μM). Cells were grown as 2D adherent monolayers overnight and then treated for 72 h. Results represent mean values ± SD, n = 3. (C) DSS 3 measuring the effects of AMG-510 (0.6–40 μM), vemurafenib (0.3–20 μM), prostratin (0.6–80 μM), OphA (0.3–20 μM), and 1 (1.3–80 μM). Cells were grown as 3D spheroids for 72 h then treated with compounds for another 72 h before alamarBlue viability measurements. Data represent mean values ± SD, n ≥ 2. (D) Heatmap of ATARiS gene sensitivity scores obtained from the project DRIVE database for KRAS-dependent cell lines (MIA PaCa-2, NCI H358, and MDA-MB-231) and HRAS-dependent cell lines (Hs 578T and T24). Negative values (red) indicate sensitivity of the cell line proliferation to the knockdown of shown genes, while positive (blue) indicates the opposite.
Amg 510, supplied by Amgen, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/amg+510/510+amg/10__1158_slash_2159___8290__cd___nd2019___012-17-4-6
Average 86 stars, based on 1 article reviews
amg 510 - by Bioz Stars, 2026-10
86/100 stars
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amg 510  (AstraZeneca ltd)
90
AstraZeneca ltd amg 510
Benchmarking of top compound 1 in several cancer cell lines. (A) The relative 2D viability of various cell lines following single dose treatment <t>with</t> <t>AMG-510</t> (1 μM), calmidazolium (2.5 μM), OphA (1 μM), and 1 (10 μM) was assessed using the alamarBlue assay. Cells were grown as 2D adherent monolayers overnight and then treated for 72 h with indicated compounds. Data represent mean values ± SD, n ≥ 3. (B) DSS 3 measuring the effects of AMG-510 (0.003–40 μM), calmidazolium (0.3–40 μM), OphA (0.3–40 μM), and 1 (0.6–80 μM). Cells were grown as 2D adherent monolayers overnight and then treated for 72 h. Results represent mean values ± SD, n = 3. (C) DSS 3 measuring the effects of AMG-510 (0.6–40 μM), vemurafenib (0.3–20 μM), prostratin (0.6–80 μM), OphA (0.3–20 μM), and 1 (1.3–80 μM). Cells were grown as 3D spheroids for 72 h then treated with compounds for another 72 h before alamarBlue viability measurements. Data represent mean values ± SD, n ≥ 2. (D) Heatmap of ATARiS gene sensitivity scores obtained from the project DRIVE database for KRAS-dependent cell lines (MIA PaCa-2, NCI H358, and MDA-MB-231) and HRAS-dependent cell lines (Hs 578T and T24). Negative values (red) indicate sensitivity of the cell line proliferation to the knockdown of shown genes, while positive (blue) indicates the opposite.
Amg 510, supplied by AstraZeneca ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/amg+510/amg+510/pm32101243-36-16-37
Average 90 stars, based on 1 article reviews
amg 510 - by Bioz Stars, 2026-10
90/100 stars
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amg 510  (Stratech Scientific Ltd)
86
Stratech Scientific Ltd amg 510
Benchmarking of top compound 1 in several cancer cell lines. (A) The relative 2D viability of various cell lines following single dose treatment <t>with</t> <t>AMG-510</t> (1 μM), calmidazolium (2.5 μM), OphA (1 μM), and 1 (10 μM) was assessed using the alamarBlue assay. Cells were grown as 2D adherent monolayers overnight and then treated for 72 h with indicated compounds. Data represent mean values ± SD, n ≥ 3. (B) DSS 3 measuring the effects of AMG-510 (0.003–40 μM), calmidazolium (0.3–40 μM), OphA (0.3–40 μM), and 1 (0.6–80 μM). Cells were grown as 2D adherent monolayers overnight and then treated for 72 h. Results represent mean values ± SD, n = 3. (C) DSS 3 measuring the effects of AMG-510 (0.6–40 μM), vemurafenib (0.3–20 μM), prostratin (0.6–80 μM), OphA (0.3–20 μM), and 1 (1.3–80 μM). Cells were grown as 3D spheroids for 72 h then treated with compounds for another 72 h before alamarBlue viability measurements. Data represent mean values ± SD, n ≥ 2. (D) Heatmap of ATARiS gene sensitivity scores obtained from the project DRIVE database for KRAS-dependent cell lines (MIA PaCa-2, NCI H358, and MDA-MB-231) and HRAS-dependent cell lines (Hs 578T and T24). Negative values (red) indicate sensitivity of the cell line proliferation to the knockdown of shown genes, while positive (blue) indicates the opposite.
Amg 510, supplied by Stratech Scientific Ltd, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/amg+510/510+amg/bio_rxiv__64898__2026__05__06__723208-182-49-50
Average 86 stars, based on 1 article reviews
amg 510 - by Bioz Stars, 2026-10
86/100 stars
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amg 510  (Biosynth Carbosynth)
N/A
KRAS G12C inhibitor. KRAS G12C inhibitor.
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amg 510  (Cayman Chemical)
N/A
AMG 510
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amg 510  (Tocris)
N/A
AMG 510
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amg-510  (1PlusChem LLC)
N/A
AMG-510
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Image Search Results


Benchmarking of top compound 1 in several cancer cell lines. (A) The relative 2D viability of various cell lines following single dose treatment with AMG-510 (1 μM), calmidazolium (2.5 μM), OphA (1 μM), and 1 (10 μM) was assessed using the alamarBlue assay. Cells were grown as 2D adherent monolayers overnight and then treated for 72 h with indicated compounds. Data represent mean values ± SD, n ≥ 3. (B) DSS 3 measuring the effects of AMG-510 (0.003–40 μM), calmidazolium (0.3–40 μM), OphA (0.3–40 μM), and 1 (0.6–80 μM). Cells were grown as 2D adherent monolayers overnight and then treated for 72 h. Results represent mean values ± SD, n = 3. (C) DSS 3 measuring the effects of AMG-510 (0.6–40 μM), vemurafenib (0.3–20 μM), prostratin (0.6–80 μM), OphA (0.3–20 μM), and 1 (1.3–80 μM). Cells were grown as 3D spheroids for 72 h then treated with compounds for another 72 h before alamarBlue viability measurements. Data represent mean values ± SD, n ≥ 2. (D) Heatmap of ATARiS gene sensitivity scores obtained from the project DRIVE database for KRAS-dependent cell lines (MIA PaCa-2, NCI H358, and MDA-MB-231) and HRAS-dependent cell lines (Hs 578T and T24). Negative values (red) indicate sensitivity of the cell line proliferation to the knockdown of shown genes, while positive (blue) indicates the opposite.

Journal: Frontiers in Cell and Developmental Biology

Article Title: A Covalent Calmodulin Inhibitor as a Tool to Study Cellular Mechanisms of K-Ras-Driven Stemness

doi: 10.3389/fcell.2021.665673

Figure Lengend Snippet: Benchmarking of top compound 1 in several cancer cell lines. (A) The relative 2D viability of various cell lines following single dose treatment with AMG-510 (1 μM), calmidazolium (2.5 μM), OphA (1 μM), and 1 (10 μM) was assessed using the alamarBlue assay. Cells were grown as 2D adherent monolayers overnight and then treated for 72 h with indicated compounds. Data represent mean values ± SD, n ≥ 3. (B) DSS 3 measuring the effects of AMG-510 (0.003–40 μM), calmidazolium (0.3–40 μM), OphA (0.3–40 μM), and 1 (0.6–80 μM). Cells were grown as 2D adherent monolayers overnight and then treated for 72 h. Results represent mean values ± SD, n = 3. (C) DSS 3 measuring the effects of AMG-510 (0.6–40 μM), vemurafenib (0.3–20 μM), prostratin (0.6–80 μM), OphA (0.3–20 μM), and 1 (1.3–80 μM). Cells were grown as 3D spheroids for 72 h then treated with compounds for another 72 h before alamarBlue viability measurements. Data represent mean values ± SD, n ≥ 2. (D) Heatmap of ATARiS gene sensitivity scores obtained from the project DRIVE database for KRAS-dependent cell lines (MIA PaCa-2, NCI H358, and MDA-MB-231) and HRAS-dependent cell lines (Hs 578T and T24). Negative values (red) indicate sensitivity of the cell line proliferation to the knockdown of shown genes, while positive (blue) indicates the opposite.

Article Snippet: AMG-510 , MedChem Express , HY-114277.

Techniques: Alamar Blue Assay, Knockdown